• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    THE METHOD OF MANUFACTURING A DYGNOSTIC MEANS TO DETERMINE THE CONTENT IN LIQUIDS OF SUBSTANCES, Bioija mixing solution, or dispersion of film-forming substance selected from the group of polyacrylates, polyacrylamides, polyvinnles, polystyrene. J. st; -: LP.- .; Shch1 sh .-: ---: cl. rolls, copolymers of butadiene, styrene or esters of aleic acid and vinyl acetate, natural polymers with active reagents and auxiliary materials and substances necessary for determining the components of biological fluids, drying with warm air and fixing the film on the carrier, if necessary, and with it, that, in order to increase the sensitivity and specificity of the method, when mixing the reagents, the addition | 1 film blower selected from cellulose, kieselguhr, silica gel, gypsum, calcium carbonate, kaolin, polyamide, glass, and baking powder (L film taken to film-forming substance in the ratio
    公开号:SU1158052A3
    申请号:SU802891753
    申请日:1980-03-10
    公开日:1985-05-23
    发明作者:Фогель Петер；Браун Ханс-Петер；Бергер Дитер；Вернер Волфганг
    申请人:Берингер Маннхайм Гмбх (Фирма)；
    IPC主号:
    专利说明:

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    € hp J The invention relates to biochemistry, namely, to the field of analytical chemistry, and can be used to investigate test liquids, such as blood, serum, urine, etc. The method of qualitative and quantitative analysis of liquids by using films However, these films cannot be used to determine cellular constituents or large molecules, such as enzymes. Such substances do not penetrate the film or do not penetrate it sufficiently to cause the necessary reaction. For this reason, it is not possible to use films in determining, for example, hemoglobin, cholesterol in lipoproteins or enzymes. The aim of the invention is to increase the sensitivity and specificity of the method. This goal is achieved in that according to the method of making a diagnostic agent for determining the content of substances in liquids, including mixing a solution or dispersion of a film-forming substance selected from the group of polyacrylates, polyacrylate IDA, polyvinyls, polystyrenes, butadiene copolymers, styrene or maleine esters or polystyrenes. vinylacetate, natural Lime with active reagents and auxiliary substances necessary for determining the components of biological fluids, drying with warm air in spirit and, if necessary, fixing the film on a carrier; when mixing the reagents, film baking powder is additionally introduced; selected from the group cellulose, diatomaceous earth, silica gel, gypsum, calcium carbonate, kaolin, polyamide, glass, and the film disintegrant is taken to film-forming substance in a ratio (0.520 ):(one). The method is carried out as follows. ., The film former is used in the form of aqueous dispersions, as well as in organic solvents. Dispersions or solutions are applied in a uniform layer onto the substrate. after drying with a waterproof film. Drying npi - starter with warm air. The reagents necessary for a definitive reaction are, as a rule, not injected in the dispersion, but the formed film can be impregnated with them. After each impregnation, warm air is used. The film disintegrant is introduced in the form of fine particles into an aqueous dispersion or organic solution of film-forming substances. The test liquid is applied to the resulting reactive layer. The excess of the material under study is washed off after some time of interaction. Defined by substances emitted by color reactions. Example 1. To determine hemoglobin in the blood, a film with diatomaceous earth in relation to a 0.5: G film former was made. The mixture was applied to the polyester film with a layer thickness and then dried with warm air. A drop of a series of dilutions of blood with different hemoglobin content is affected for 1 minute and after washing the drop with cotton wool a gamut of staining is obtained. You get a stable film with a slight staining. Example 2. The determination is carried out according to Example 1; Kieselguhr is added in the ratio to the film former 1: 1. You get a stable film with a uniform reaction across its surface. Example 3. The determination is carried out according to Example 1. The baking powder (gypsum) is added to the film former in a 10: 1 ratio. In this case, a stable film is formed, giving a deep uniform staining in the hemoglobin blood test. Example 4. The determination is carried out as in Example 1. The baking powder (gypsum) is added to the film former in a ratio of 20: 1. In this case, a stable film is formed, giving uniform staining during the examination of blood for hemoglobin. The invention allows the spatial separation of the constituent parts of the test liquid, with the components of the mixture being distributed over different layers.
    311580524
    Depending on the film, the suction film can be changed due to the particle IMMR sizes, creating a multilayer binder ratio and a captive system. Absorbing co-agent ability.
    权利要求:
    Claims (1)
    [1]
    METHOD FOR MAKING A DIAGNOSTIC MEANS FOR DETERMINING THE CONTENT IN LIQUIDS OF SUBSTANCES, including mixing a solution or dispersion of a film-forming substance selected from the group polyacrylates, polyacrylamides, polyvinyls, polystyrenes, butadiene copolymers, styrene or polyamino acid esters and auxiliary substances necessary for determining the components of biological fluids, drying with warm air and, if necessary, fixing and on the carrier, with teM, which, in order to increase the sensitivity and specificity of the method, when mixing the reagents, a film baking powder selected from the group of cellulose, kieselguhr, silica gel, gypsum, calcium carbonate, kaolin is added , polyamide, glass, and the baking powder of the film is taken to the film-forming substance in the ratio (0.5-20) :( 1).
    SU .... 1158052>
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    同族专利:
    公开号 | 公开日
    AR221529A1|1981-02-13|
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    YU43936B|1989-12-31|
    EP0016387B1|1983-01-26|
    JPS55125453A|1980-09-27|
    YU65080A|1988-08-31|
    CA1129323A|1982-08-10|
    YU44816B|1991-02-28|
    AU513751B2|1980-12-18|
    EP0016387A1|1980-10-01|
    DD149122A5|1981-06-24|
    IE800501L|1980-09-15|
    AU5633580A|1980-09-18|
    FI800726A|1980-09-16|
    AT2359T|1983-02-15|
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    FI71202B|1986-08-14|
    DK163264B|1992-02-10|
    JPH0248863B2|1990-10-26|
    US4312834A|1982-01-26|
    DE3061725D1|1983-03-03|
    FI71202C|1986-11-24|
    DK163264C|1992-07-06|
    YU183584A|1986-10-31|
    CS243453B2|1986-06-12|
    DK101880A|1980-09-16|
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    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    DE19792910134|DE2910134A1|1979-03-15|1979-03-15|DIAGNOSTIC AGENT FOR DETECTING COMPONENTS OF BODY LIQUIDS|
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